DNA isolation for the highest demands: Simple extraction & purification of nucleic acids
Kits and instruments that let you extract and purify DNA and RNA without centrifuging.
Innovative kits and automation solutions for your RNA & DNA extractions
Beckman Coulter’s extraction and purification kits let you benefit from the Solid Phase Reversible Immobilization (SPRI) technology. It involves the use of paramagnetic beads that selectively bind nucleic acids such as DNA and/or RNA according to type and size. For your work routines, this means that you do not have to centrifuge during DNA isolation or RNA extraction, neither must you carry out complex filtration steps. SPRI thus enables safe and high-performance isolation and purification protocols for demanding molecular biology applications including qPCR, ddPCR, Sanger sequencing, Next-Gen Sequencing (NGS) and microarrays.
In combination with one of the semi-automatic and/or automatic instrument solutions described below, you can efficiently clean up even the most difficult matrices while reducing error rates and achieving high yields.
This is how nucleic acid purification using SPRI works:
Step 1:
Immobilization of the nucleic acid. SPRI beads are added to the sample. Contained DNA or RNA binds selectively to the paramagnetic beads while impurities remain in the solution.
Step 2:
Purification/washing. A magnet pulls the microparticles out of the solution. The solution is discarded and the microparticles washed to obtain high purity nucleic acid.
Step 3:
Elution. The purified DNA or RNA is eluted under aqueous conditions, resulting in high-purity nucleic acids and maximum flexibility for your subsequent applications.
Beckman Coulter offers the optimal solution for any application:
- DNA extraction and purification
- RNA isolation and purification
- Total nucleic acids (RNA and DNA isolation combined)
- Dye terminator removal
- Fragment size selection for NGS library construction
Work more effectively: How to take your nucleic acid workflows to the next level
Kits to extract & purify nucleic acids
Genomics Reagents
- DNA extraction
- Isolation of cell-free DNA
- RNA extraction
- Total nucleic acid extraction with high yields
- Purification & size selection
Automate your workflow & expand flexibly
Biomek i5 Nucleic Acid Solutions
- Automation solution based on the plug-and-play principle
- Liquid handling workstation with 96 channels and up to 25 positions
- Either as a stand-alone solution for purification only …
- … or flexibly expandable for automated extraction
You have questions or want to optimize your application?
Our application team will answer any of your questions about DNA isolation and RNA extraction. We are happy to adapt our reagents to your individual needs. To do so we work with your samples or similar sample material to optimize our Agencourt kits for you and to provide your lab with the best possible solution for RNA or DNA isolation. Simply fill in the following contact form if you have any questions about RNA or DNA extraction or if you would like to test our application service. An application expert will contact you to discuss your individual requirements.
Biomek NGeniuS Next Generation Library Prep System and demonstrated applications are not intended or validated for use in diagnostic procedures.
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