DNA isolation for the highest demands: Simple extraction & purification of nucleic acids

Kits and instruments that let you extract and purify DNA and RNA without centrifuging.

Innovative kits and automation solutions for your RNA & DNA extractions

Beckman Coulter’s extraction and purification kits let you benefit from the Solid Phase Reversible Immobilization (SPRI) technology. It involves the use of paramagnetic beads that selectively bind nucleic acids such as DNA and/or RNA according to type and size. For your work routines, this means that you do not have to centrifuge during DNA isolation or RNA extraction, neither must you carry out complex filtration steps. SPRI thus enables safe and high-performance isolation and purification protocols for demanding molecular biology applications including qPCR, ddPCR, Sanger sequencing, Next-Gen Sequencing (NGS) and microarrays.

In combination with one of the semi-automatic and/or automatic instrument solutions described below, you can efficiently clean up even the most difficult matrices while reducing error rates and achieving high yields.

This is how nucleic acid purification using SPRI works:

Step 1:
Immobilization of the nucleic acid. SPRI beads are added to the sample. Contained DNA or RNA binds selectively to the paramagnetic beads while impurities remain in the solution.

Step 2:
Purification/washing. A magnet pulls the microparticles out of the solution. The solution is discarded and the microparticles washed to obtain high purity nucleic acid.

Step 3:
Elution. The purified DNA or RNA is eluted under aqueous conditions, resulting in high-purity nucleic acids and maximum flexibility for your subsequent applications.

Beckman Coulter offers the optimal solution for any application:

  • DNA extraction and purification
  • RNA isolation and purification
  • Total nucleic acids (RNA and DNA isolation combined)
  • Dye terminator removal
  • Fragment size selection for NGS library construction
NGeniuS

An Evolutionary Leap in NGS Liquid-Handling Systems

Discover the new Biomek NGeniuS Next Gen Library Prep System with its error-reduction technology, reduced hands-on time, and flexibility. This automated NGS workstation is compatible with an array of library preparation kits from multiple vendors and has a user-friendly interface that requires no programming skills. With an integrated thermal cycler, labware transport and reagent aliquoting, it increases the walk-away time and can process up to 24 samples at a time.

Work more effectively: How to take your nucleic acid workflows to the next level

Kits to extract & purify nucleic acids

Genomics Reagents

Kits to extract & purify nucleic acids - Genomics Reagents
  • DNA extraction
  • Isolation of cell-free DNA
  • RNA extraction
  • Total nucleic acid extraction with high yields
  • Purification & size selection

Effective purification with no need to centrifuge

EMnetik 24

Effective purification with no need to centrifuge - Emnetik 24

Automate your workflows & expand flexibly

Biomek i5 Nucleic Acid Solutions

Automate your workflows & expand flexibly - Biomek i5 Nucleic Acid Solutions
  • Automation solution based on the plug-and-play principle
  • Liquid handling workstation with 96 channels and up to 25 positions
  • Either as a stand-alone solution for purification only …
  • … or flexibly expandable for automated extraction

Automated preparation of NGS libraries

Biomek NGeniuS

Automated preparation of NGS libraries - Biomek NGeniuS
  • Flexible, easy-to-use liquid handling workstation for NGS library preparation
  • Increased walk-away time
  • Processes up to 24 samples at the same time
  • Multiple applications demonstrated

You have questions or want to optimize your application?

Our application team will answer any of your questions about DNA isolation and RNA extraction. We are happy to adapt our reagents to your individual needs. To do so we work with your samples or similar sample material to optimize our Agencourt kits for you and to provide your lab with the best possible solution for RNA or DNA isolation. Simply fill in the following contact form if you have any questions about RNA or DNA extraction or if you would like to test our application service. An application expert will contact you to discuss your individual requirements.

Biomek NGeniuS Next Generation Library Prep System and demonstrated applications are not intended or validated for use in diagnostic procedures.

©2022 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the Stylized Logo, and Beckman Coulter product and service marks mentioned herein, including Biomek and Biomek NGeniuS, are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. All other trademarks are the property of their respective owners.

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NOT ALL PRODUCTS ARE AVAILABLE IN ALL COUNTRIES.
PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS

The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.

© 2000 - 2024 Beckman Coulter, Inc. All rights reserved. Beckman Coulter, the stylized logo, and the Beckman Coulter product and service marks mentioned herein are trademarks or registered trademarks of Beckman Coulter, Inc. in the United States and other countries. All other trademarks are the property of their respective owners.