Accelerate Your Microbial Bioprocess Development With High-Throughput Fermentation
The BioLector XT Microbioreactor offers automatable fed-batch cultivations with integrated biomass, pH & DO monitoring
Scale-up is the bottleneck in bioprocess development. It takes a lot of time, drastically slowing down early stage development and thus the path to the final product. From early screening experiments in shake flasks to smaller fermenters to production scale, your processes can take days or weeks.
You can, of course, reduce the time by using multiple fermenters simultaneously. But this is limited by your available space, human resources and budget. Imagine how costly it would be to run 32, or even 48, parallel fermentations in sizable fermenters.
Now imagine if you achieve such a throughput with only 7 hours of hands-on time
The BioLector XT Microbioreactor lets you do just that, helping to massively accelerate your bioprocess development so you can spend more valuable time on other tasks.
This high-throughput microbial fermentation system enables you to rapidly evaluate biomass, pH, dissolved oxygen (DO), fluorescence, and other key cultivation parameters.
Supporting a diverse range of microbes across varied temperature, light, and gassing conditions, the BioLector XT Microbioreactor streamlines early-stage screening and process characterization workflows for a de-risked scale-up.
This is how many fermentations you can run in a week:
10 – 50
using shake flasks
48 – 240
using the BioLector XT Microbioreactor
4 – 8
using fermenters
The advantages of the BioLector XT Microbioreactor:
- High-Throughput: Run 48 batch or 32 fed-batch fermentations in a single microtiter plate.
- pH Control: Manage the pH of wells with pre-calibrated optical sensors.
- Superior Data Quality: Continuous monitoring improves reproducibility and reduces human error.
- Microbial Versatility: Cultivate phototrophic*, anaerobic, and aerobic microbes from bacteria to fungi.
- Automatable for complex experiment designs (DoE), sampling and more.
* Requires optional Light Array Module
Video Watch the BioLector XT Microbioreactor in action
Boost your bioprocessing workflow in other applications:
- Growth parameter optimization
- Growth characterization
- Bioprocessing scale-up
- Vaccine development (including mRNA vaccine development)
- High-throughput protein expression
- Adeno-Associated Virus (AAV) Plasmid generation
- Anaerobic / aerobic / microaerophilic fermentations
The BioLector XT Microbioreactor integrates with the Biomek i5 platform for fully automated high-throughput bioprocessing — enabling autonomous media prep, cultivation monitoring, and timed addition of inducers or feed solutions based on real-time signals.
Automated sampling into temperature-controlled positions supports precise monitoring and control, whether optimizing plasmid production or refining protein expression in bacterial or fungal systems. Sampling occurs without disrupting the shaking motion, ensuring optimal gas transfer and mixing throughout the cultivation process.